Pickens Homes with Mixed Use Style

Welcome to Pickens, South Carolina – a charming town nestled in the heart of the Blue Ridge Mountains, where Southern hospitality meets stunning natural beauty. Known for its rich history and vibrant community, Pickens offers a delightful blend of small-town charm and modern conveniences, making it an ideal place to call home.

The city boasts an array of recreational activities, from hiking the scenic trails of the nearby Table Rock State Park to enjoying local festivals that celebrate the town's heritage. With a population that values community spirit, Pickens is home to friendly neighbors, excellent schools, and a variety of local shops and eateries that contribute to its unique character.

One of the most appealing aspects of Pickens is its diverse housing options, particularly the homes with mixed-use style. These properties are designed to accommodate both residential and commercial spaces, allowing residents to live where they work or enjoy the convenience of nearby amenities. Imagine waking up in a cozy, stylish home just steps away from your favorite café or boutique – a lifestyle that combines comfort with practicality.

Whether you’re a first-time homebuyer, a growing family, or looking to invest in a vibrant community, Pickens offers a range of mixed-use properties that cater to various lifestyles. With its picturesque surroundings, rich local culture, and a welcoming atmosphere, Pickens is not just a place to live; it’s a place to thrive. Discover the magic of this lovely town and find your perfect mixed-use home today!

Newest Pickens Homes with Mixed Use Style

$995,000

3 Beds ⋅ 2.5 Baths

I am pleased to present a unique real estate opportunity in the heart of Upstate South Carolina: a beautiful traditional home accompanied by the turnkey Laurel Mountain Inn. The custom-built primary residence features over 2,300 square feet of craftsmanship with an open floor plan, a main-level primary bedroom, three bedrooms, 2.5 bathrooms, and an attached office. The property also includes a full walkout basement ready to be finished as additional living space or a rental unit. The adjacent Laurel Mountain Inn sits on nearly seven acres next to Table Rock State Park. This fully operational, five-room income-producing property comes with a complete vendor list and an excellent reputation. Situated off Scenic Highway 11 near Caesars Head and Lake Keowee, it is a premier destination for nature enthusiasts and an ideal investment for hospitality entrepreneurs or event venue developers. While offering a private mountain lifestyle, the property remains conveniently located 30 minutes from Travelers Rest and 45 minutes from downtown Greenville. Showings are limited to qualified buyers and require a minimum 3-hour notice.

133 Hiawatha Trail, Pickens

$689,000

2 Beds ⋅ 1 Baths

Tons of options with this new property featuring 23+ acres of mature forests with a new garage/ cabin combo. You can live in it as-is, or live in it while you built your main home, then use the current home as a guest house. The home is built with heavy duty all wood construction, but the walls are not load bearing, so you could take all of them out and convert the entire building into a workshop/ garage, or eliminate the garage and turn it all into living space. It would be great as a garage as the floors are 6" thick concrete, with 12' ceilings, plus its wired for heavy duty 220 garage appliances. The property offers 3 creeks, hardwood forests, multiple gardens with a solar powered creek watering system, ATV/ bike trails, walking paths along the creek. This property would serve as a great multifamily compound or as a ranch. Its unrestricted, so use your imagination. The property goes up the hill and has a great homesite with panoramic views .

3306 Moorefield Memorial Highway, Pickens

$295,000

3 Beds ⋅ 2 Baths

Rare Mixed-Use Investment on Moorefield Memorial Highway — Pickens, SC Don't miss this rare multi-use gem in a prime, high-visibility location on a major highway with approximately 7,000 vehicles passing daily! Just a few blocks from the Pickens County offices, this versatile property is ideal for investors seeking dual rental income or an owner-operator who wants to live and work under one roof. First Floor: Two office spaces plus a large reception area — perfect for a professional practice, storefront, or business headquarters. Also includes a small galley kitchen, full bathroom, and a utility room with laundry hookups. Second Floor: A charming one-bedroom apartment with its own full bathroom, kitchen, and living area. A long-term tenant is already in place, offering immediate rental income or a ready-made additional workspace. Whether you're looking to grow your investment portfolio or find a space where business and life come together, this property checks every box. All information is deemed accurate but not guaranteed.

4612 Moorefield Memorial Highway, Pickens

$280,000

1 Baths

Storybook property with right on the Oolenoy River. There are numerous options with this property, it features an office/ efficiency apartment with a single car garage that could be finished into a bedroom. You could build onto this or keep it as-is while you built your new home. It could also be a guest quarters or maybe a weekend rental. The land is mostly pasture, so it would be great as a farm, campground, maybe a music venue, or even a combination of all of these. This property features 3.2 acres, but the best feature of this property is the beautiful and relaxing sound of the rushing waters of the river. It also has a very nice creek running along the full length of the property that joins the river. All of this is right in the heart of one of the most beautiful parts of the Upstate and nestled at the foot of the mountains.

716 Sliding Rock Road, Pickens

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The Listings data contained on this website comes from various participants of The Multiple Listing Service of Greenville, SC, Inc. Internet Data Exchange. IDX information is provided exclusively for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The properties displayed may not be all the properties available. All information provided is deemed reliable but is not guaranteed. © 2026 Greater Greenville Association of REALTORS®. All Rights Reserved. Last Updated